Thursday, May 26, 2016

 

Interesting Facts on Jewish Ashkenazi DNA

Nadene Goldfoot                                            

On IBDs.  Identical by Descent.  
Gusev et al (2011) reported that in Ashkenazi Jews “the entire segment of chromosome 6, between 25 and 35 Mb (megabases-a unit of physical distance) , is shared among individuals unrecombined at least 4-fold more than any other region in the genome”.

Peaks of IBD sharing over 5 cMs in size were seen on chromosomes 9 and 19 in Ashkenazi Jews.

AncestryDNA analysed the matches of over half a million US customers genotyped on an Illumina OmniExpress chip (~700,000 SNPs) and found that in certain regions of the genome hundreds and sometimes thousands of people were predicted to share DNA with each other. The problem was particularly pronounced in customers of Jewish ancestry and in some people of Hispanic descent, but the problem was observed across all ethnic groups. They concluded that these regions of identical DNA were likely to be attributed to a shared ethnic history rather than recent common ancestry. 

Segment size:
30 cMs 0f a segment stands a 90% chance of coming from 6 generations ago
20-30 cMs                               50%
12-20 cMs                               20%
6-12 cMs                                  5%
6 cMs                                       1%  

In a study of a European subset of the Population Reference Sample (POPRES) dataset it was estimated that for the most part IBD blocks

 longer than 4 cM come from 500 to 1,500 years ago, and blocks

 longer than 10 cM are within the last 500 years.

I"ll look for blocks of 10cMs or more to hope to find a common ancestor.  However, "In general it will be difficult to find the genealogical connection with the majority of your matches under about 15 cMs." Then let's hope to find segments of 20 cMs or more for matches.  
Resource: http://isogg.org/wiki/Identical_by_descent

The techniques of triangulation, chromosome mapping, and phasing can be used to distinguish between IBD segments and non-IBD segments. 

Triangulation was used in the Halpern & Branches group of FTDNA.  through GedMatch.com .  http://isogg.org/wiki/Identical_by_state 

The blog article by Ann Turner, https://segmentology.org/2015/10/02/anatomy-of-an-ibs-segment/, tells how to triangulate.  Besides that, it explains much more.  One needs to study this.  
More on :
http://dna-footprints.com/the-abcs-of-dna-ibd-vs-ibs/.

When we have a DNA segment that matches another person we cannot be sure that it is a real match unless it is also a match to a third person who matches both of us at that spot. This is called triangulation.  http://blog.kittycooper.com/2014/10/when-is-a-dna-segment-match-a-real-match-ibd-or-ibs-or-ibc/

So many questions come up with very wee segments that are shared.  What does it mean?  This is for all people, not just Ashkenazi Jews:  http://isogg.org/wiki/Autosomal_DNA_statistics.  Below shows the % shared between these distant cousins.   These are not even of 1.0cM but less.

0.000763%0.05cMs8th cousinsDegree 17
 
0.001525%0.10cMs7th  cousins once removedDegree 16

Small segments are prone to be false positives.  What out.  There is too much uncertainty surrounding small segments to base any conclusion on them.  The researchers found that more than 67% of all reported segments shorter than 4 cM are false-positive segments (see FIG. 2B, below).   At least 60% of 4cM segments were false-positive, and at least 33% of 5 cM segments were false-positive. The number of false-positives decreased fairly rapidly above 5 cM.
http://thegeneticgenealogist.com/2014/12/02/small-matching-segments-friend-foe/

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Monday, May 02, 2016

 

Goldfoot Q-L245 Y (Q-BZ67) Haplogroup Matches With Autosomal Familyfinder DNA

Nadene Goldfoot                                                            
Figuring out who 4th cousins can be
  


Goldfoot Q-L245 (now updated to be QBZ67 as of 5/30/16)  Y haplogroup does have matches with the same individuals found in familyfinder.  Evidently it had become Q-YP1003.  After SNP tests, or were the the STR tests of upgrading, the twig of this line have been the QBZ67, BZ64 and BZ68.  I believe these are all Jewish lines.

"Haplogroup Q is the lineage that links Asia and the Americas. This lineage is found in North and Central Asian populations, as well as native Americans. Among European populations, haplogroup Q is most frequently found in Eastern Europe and Scandinavia. This lineage is believed to have originated in Central Asia and migrated through the Altai/Baikal region of northern Euras." 

Some of the results are as follows:  All have had the 67 allele Y dna test.  I found that though the original male tester may not have an allele dna match, someone in his family may match with the haplogroup match.

In other words, many of the men who match Nathan Goldfoot's grandson by Q's Y haplogroup, also are found to match him with chromosome segments in the autosomal familyfinder tet from FTDNA.
                                                                      
Nathan Abraham Goldfus-Goldfoot b: August 5, 1872 Telsiai, Kaunas, Lithuania-Q-L245
d: July 19, 1912-accidently in Portland, Oregon, USA., grandfather of tested Goldfoot.

His test of SNPs has now been upgraded to be called Q-BZ67 as of 5/26/16.    
1. Distance of 7 steps: with Q-M242.  5 people of Goldfoot family-4th cousins, 5th cousins

2. Distance of 7 steps with Q-M378.  sister of Q tested matched

3. Distance of 7 steps with Q-M378  1st cousin on paternal side matched 5th cousin

4. Distance of 7 steps with Q-YP1009 (possibly Romanian origin) sister and 1st cousin matched, 4th cousin

5. Distance of 7 steps with Q-YP1009 sister as 5th cousin and 1st cousin matched 4th cousin

6. Distance of 7 steps with Q-M378  Germany origin, nephew of 1st cousin matched as 5th cousin
                                                               
A few of these above were listed with a distance of 4 steps  before being tested with all 67 alleles.  Then the distance was more-going to 7 steps.    

7.* Latest discovery from Rebekah Canada via project leader,  Janet Akaha,  is that Q-Y2200 is exclusively Ashkenazic Jewish, forming 95% confidence between the years of 1250 BCE and 50 BCE. This comes from results of SNP Pack.

Y2754 branch -if sharing an Oppenheimer surname as early as 1440 CE, all would share an ancestor well before having this surname.  We do match with Oppenheimers.  Oppenheimer is the deepest pedigree in project.              
Children International Folk Dancers of Telsiai, Kaunas, Lithuania
Found was a Goldfoot, with a distance of 3 steps who has the same surname as our Goldfoot.  I was able to trace our grandfather, Nathan Abraham Goldfoot, to Dublin, Ireland where he stayed with a relative  of the newly found Goldfoot. (In 1893 Nathan stayed with Stanley's Goldfoot's parents house in Dublin.  This is where my grandfather, Nathan,  also stayed! The address was 13 Arbutus Place, SCR, Dublin, South, Ireland.) Then he left for Winnipeg, Canada which led eventually to the USA.  Otherwise, none by a distance of 7 shared the same surname.
                                                                         
Council, Idaho area-mountainous mining town, now on the way to
lake resort. 
     
Johannesburg, South Africa
This branch of the Goldfoot family went from Dublin to South Africa.  Other Q haplogroups are also in South Africa.

It has been found that the branch of people on the human tree called Q-L245 happened 4500 years ago, which would bring us to the year 2484 BCE.   That was before King Saul's days who lived in the 11th century BCE.  Moses, who led the Jews out of Egypt, did so in c1191 BCE.  (He was born in 1391BCE and died at age 120 in 1271 BCE).  That means that Jacob and his family of 70 had entered Egypt in 1591 BCE, so the family of Abraham that had reached the city of Ur, now in Iraq, had started from the East around the Tigris and Euphrates Rivers of Mesopotamia back in 2484 BCE, which is logical.

 Q-L245 is a branch off of a more original Q branch, so already by this time it's a pretty old branch.  A more refined branch that our Goldfoot's have found themselves on might be the Q-YP1009 which was  formed 1200 years ago (ybp-years before present) or  the year of 816 CE.  By then, Jews had been entering into Lithuania in the 700s from Germany and France.  Our Goldfoot line came from Telsiai, Lithuania as far as we know, where many Goldfus were found from records that are retrievable.  The time of our most recent common ancestor (the TMRCA) was 650 years ago or the year 1360.  Things were heating up for the Jews by then as the Christian leaders would be expelling them from Spain in 1492, and that would alter the attitudes of all the monarchs against Jews.  .


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